Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685753 | 1.00 | AOC3 (0.54) | AOC3SLC6A4SLC6A2SLC6A3ALOX15 | |
| SCHEMBL7197211 | 0.89 | AOC3 (0.51) | AOC3SLC6A4SLC6A2SLC6A3ALOX15 | |
| SCHEMBL31737779 | 0.84 | AOC3 (0.58) | AOC3SLC6A4SLC6A2SLC6A3ALOX15 | |
| SCHEMBL5662767 | 0.82 | AOC3 (0.56) | AOC3SLC6A4SLC6A2ALOX15ADRB2 | |
| SCHEMBL6094770 | 0.82 | AOC3 (0.37) | AOC3SLC6A4SLC6A2UTS2RALDH1A1 | |
| SCHEMBL7113377 | 0.81 | AOC3 (0.42) | AOC3SLC6A4SLC6A2SLC6A3ALOX15 | |
| SCHEMBL21198899 | 0.81 | AOC3 (0.59) | AOC3SLC6A4SLC6A2SLC6A3ADRB2 | |
| SCHEMBL21199033 | 0.81 | AOC3 (0.59) | AOC3SLC6A4SLC6A2SLC6A3ADRB2 | |
| SCHEMBL3650398 | 0.81 | AOC3 (0.59) | AOC3SLC6A4SLC6A2SLC6A3ADRB2 | |
| SCHEMBL10887514 | 0.81 | AOC3 (0.54) | AOC3SLC6A4SLC6A2ALOX15ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292419-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2010-11-18 | — | — | US | disclosed |