Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3421005 | 0.93 | KMT2A (0.38) | MEN1KMT2AHPGDNPSR1TMEM97 | |
| SCHEMBL3579943 | 0.92 | KMT2A (0.40) | MEN1KMT2AHPGDNPSR1TMEM97 | |
| SCHEMBL3692466 | 0.92 | MEN1 (0.36) | MEN1KMT2AHPGDNPSR1TMEM97 | |
| SCHEMBL13338188 | 0.90 | KMT2A (0.38) | MEN1KMT2AHPGDNPSR1MAPT | |
| SCHEMBL3582294 | 0.89 | KMT2A (0.41) | MEN1KMT2AHPGDNPSR1TMEM97 | |
| SCHEMBL3579178 | 0.89 | KMT2A (0.41) | MEN1KMT2AHPGDNPSR1TMEM97 | |
| SCHEMBL366030 | 0.88 | KMT2A (0.41) | MEN1KMT2AHPGDNPSR1TMEM97 | |
| SCHEMBL3580003 | 0.88 | KMT2A (0.42) | MEN1KMT2AHPGDNPSR1TMEM97 | |
| SCHEMBL2977784 | 0.87 | MEN1 (0.36) | MEN1KMT2AHPGDNPSR1ALDH1A1 | |
| SCHEMBL3418938 | 0.86 | KMT2A (0.36) | MEN1KMT2AHPGDNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010044686-A1 | AKR1C3 AS A BIOMARKER, METHODS OF SELECTING AND TREATING PATIENTS BASED UPON AN AKR1C3 PROFILE AND COMPOUNDS FOR USE THEREIN | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-04-22 | — | — | WO | disclosed |