⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24832 | 0.71 | — | — | |
| SCHEMBL10939433 | 0.69 | — | — | |
| SCHEMBL4933350 | 0.67 | — | — | |
| SCHEMBL4201234 | 0.67 | — | — | |
| SCHEMBL1664161 | 0.67 | — | — | |
| SCHEMBL208618 | 0.67 | — | — | |
| SCHEMBL9816555 | 0.67 | — | — | |
| SCHEMBL1381917 | 0.65 | — | — | |
| SCHEMBL88927 | 0.65 | — | — | |
| SCHEMBL88328 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511268-B1 | OXAZINE DERIVATIVE | SHIONOGI & CO (JP) | 2016-07-13 | — | — | EP | claimed |
| EP-2604595-B1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | SHIONOGI & CO (JP) | 2016-03-16 | — | — | EP | claimed |
| US-8859209-B2 | Reimmunization and antibody design | CARVIAR APS (DK) | 2014-10-14 | — | — | US | claimed |
| US-8420630-B2 | Pyrimidine derivatives | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2013-04-16 | — | — | US | claimed |
| EP-2465504-A1 | Novel 2,3-diamino-quinazolinone derivatives and their medical use | NeuroSearch A/S (DK) | 2012-06-20 | — | — | EP | claimed |
| EP-2090571-B1 | Pyrimidine derivates, medicaments comprising them, their use and process of their preparation | BOEHRINGER INGELHEIM PHARMA (DE) | 2012-05-16 | — | — | EP | claimed |
| US-8178544-B2 | 2, 3-diamino-quinazolinone derivatives and their medical use | NEUROSEARCH A/S (DK) | 2012-05-15 | — | — | US | claimed |
| US-20100303725-A1 | Technetium- and Rhenium-Bis(heteroaryl) Complexes, and Methods of Use Thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2010-12-02 | — | — | US | claimed |
| US-7824661-B2 | Technetium- and rhenium-bis(heteroaryl) complexes, and methods of use thereof | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2010-11-02 | — | — | US | claimed |
| US-20100160315-A1 | NOVEL 2, 3-DIAMINO-QUINAZOLINONE DERIVATIVES AND THEIR MEDICAL USE | NEURO SEARCH A/S (DK) | 2010-06-24 | — | — | US | claimed |
| WO-1999000355-A1 | NOVEL AZULENE DERIVATIVES AND MEDICAMENTS WITH A METALLOPROTEIN-INHIBITING EFFECT CONTAINING SAID DERIVATIVES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-01-07 | — | — | WO | claimed |
| WO-1999000118-A1 | USE OF AZULENE DERIVATIVES AS METALLOPROTEIN INHIBITORS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-01-07 | — | — | WO | claimed |
| EP-0887077-A1 | Use of azulene derivatives as metalloprotease inhibitors | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-30 | — | — | EP | claimed |
| EP-0887339-A1 | Azulene derivatives and medicaments containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-30 | — | — | EP | claimed |
| US-5707989-A | ANTITUMOR AGENTS, INHIBITING SIGNAL TRANSDUCTION MEDIATED BY TYROSINE KINASES | DR. KARL THOMAE GMBH (DE) | 1998-01-13 | — | — | US | claimed |
| EP-0779888-A1 | PYRIMIDO [5,4-D]PYRIMIDINES, DRUGS CONTAINING THESE COMPOUNDS, THEIR USE, AND PROCESS FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1997-06-25 | — | — | EP | claimed |
| WO-1996007657-A1 | PYRIMIDO[5,4-D]PYRIMIDINES, DRUGS CONTAINING THESE COMPOUNDS, THEIR USE, AND PROCESS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-03-14 | — | — | WO | claimed |
| US-4908368-A | SRS-A antagonist | MURASE KIYOSHI (JP) | 1990-03-13 | — | — | US | claimed |
| US-4855310-A | Thiadiazole compounds as antagonists of SRS-A | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-08-08 | — | — | US | claimed |
| US-4546176-A | 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same | EISAI CO., LTD. (JP) | 1985-10-08 | — | — | US | claimed |