Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.67 |
| ▸ | PDE4A | P27815 | 1/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693773 | 1.00 | ABCG2 (0.67) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5915734 | 0.87 | ABCG2 (0.63) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5915396 | 0.87 | ABCG2 (0.63) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3692694 | 0.86 | ABCG2 (0.68) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3687798 | 0.86 | ABCG2 (0.68) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3684007 | 0.85 | ABCG2 (0.47) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3687299 | 0.85 | ABCG2 (0.47) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3693626 | 0.84 | ABCG2 (0.58) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3688640 | 0.84 | ABCG2 (0.58) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5915651 | 0.83 | ABCG2 (0.73) | ABCG2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642367-B2 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2010-01-05 | — | — | US | disclosed |
| US-20060235073-A1 | Diamino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-10-19 | — | — | US | disclosed |