Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 12/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694049 | 0.86 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL2540969 | 0.83 | KCNH2 (0.57) | KCNH2DRD2DRD4 | |
| SCHEMBL2539634 | 0.83 | KCNH2 (0.57) | KCNH2DRD2DRD4 | |
| SCHEMBL2544571 | 0.83 | KCNH2 (0.57) | KCNH2DRD2DRD4 | |
| SCHEMBL2541646 | 0.83 | KCNH2 (0.57) | KCNH2DRD2DRD4 | |
| SCHEMBL2541650 | 0.83 | KCNH2 (0.57) | KCNH2DRD2DRD4 | |
| SCHEMBL2539637 | 0.83 | KCNH2 (0.57) | KCNH2DRD2DRD4 | |
| SCHEMBL3694796 | 0.81 | KCNH2 (0.76) | KCNH2 | |
| SCHEMBL5254892 | 0.81 | KCNH2 (0.74) | KCNH2DRD2DRD4 | |
| SCHEMBL5251668 | 0.81 | KCNH2 (0.74) | KCNH2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |
| US-7223776-B2 | Compounds with anti-bacterial activity | MORPHOCHEM AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20060040949-A1 | Novel compounds with antibacterial activity | MORPHOCHEM AG | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040949-A1 | Novel compounds with antibacterial activity | MRPL21, Q6ZSR9, MRPL19 | KCNH2 2411/4885DRD2 4147/4885DRD4 2564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.