Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3696034 | 0.94 | ITGB1 (0.32) | CNR1ITGB1ITGA4BACE1STS | |
| SCHEMBL2349106 | 0.87 | BACE1 (0.39) | BACE1 | |
| SCHEMBL3690224 | 0.87 | BACE1 (0.39) | BACE1 | |
| SCHEMBL3687462 | 0.83 | ITGB1 (0.30) | ITGB1ITGA4 | |
| SCHEMBL3688466 | 0.83 | ITGB1 (0.30) | ITGB1ITGA4 | |
| SCHEMBL2352504 | 0.82 | BACE1 (0.40) | BACE1 | |
| SCHEMBL3688178 | 0.81 | HTT (0.35) | — | |
| SCHEMBL2349221 | 0.74 | BACE1 (0.34) | BACE1STS | |
| SCHEMBL2349103 | 0.73 | BACE1 (0.40) | BACE1 | |
| SCHEMBL3688119 | 0.73 | ITGB1 (0.31) | ITGB1ITGA4BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2204373-A1 | Phosphonic acid as Plasma Carboxypeptidase B Inhibitors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-07-07 | — | — | EP | disclosed |