SCHEMBL3687204

SCHEMBL3687204

C=CCc1cccn(-c2ccc(N3C[C@H](CNC(=O)Oc4ccc(Cl)s4)OC3=O)c(F)c2)c1=O

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.58
F2 P00734 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2997712 0.90 F10 (0.71) F10F2
SCHEMBL3690092 0.86 F10 (0.60) F10
SCHEMBL2994544 0.82 F10 (0.77) F10F2
SCHEMBL3002047 0.81 F10 (0.78) F10F2
SCHEMBL2473618 0.78 F10 (0.73) F10F2
SCHEMBL3262953 0.78 F10 (0.74) F10F2
SCHEMBL3678860 0.77 F10 (0.60) F10
SCHEMBL3678642 0.77 F10 (0.60) F10
SCHEMBL3000234 0.76 F10 (0.76) F10
SCHEMBL2993951 0.76 F10 (0.69) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2167495-A1 SUBSTITUTED OXAZOLIDINONES AND THE USE THEREOF Bayer Schering Pharma AG (DE) 2010-03-31 EP disclosed
WO-2008155034-A1 SUBSTITUTED OXAZOLIDINONES AND THE USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-12-24 WO disclosed