Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883340 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL4878012 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL4875798 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL3686802 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL4883237 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL4877810 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL4880051 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL4883354 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL4873881 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL4878515 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1CES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025028496-A1 | METHOD FOR PRODUCING RUBBER COMPOSITION | 株式会社ブリヂストン | 2025-02-06 | — | — | WO | disclosed |
| US-20230211634-A1 | RUBBER MODIFIER FOR TIRE AND RUBBER COMPOSITION FOR TIRE | Harima Chemicals, lncorporated (JP) | 2023-07-06 | — | — | US | disclosed |
| CN-115667410-A | Rubber modifier for tire and rubber composition for tire | 哈利玛化成株式会社 | 2023-01-31 | — | — | CN | disclosed |
| CN-109153825-B | Tire filler, tire rubber composition, tire, method for producing tire filler, and aggregation inhibitor | 哈利玛化成株式会社 | 2021-07-20 | — | — | CN | disclosed |
| US-10947363-B2 | Filler for tires, rubber composition for tires, tire, method for producing filler for tires, and aggregation inhibitor | HARIMA CHEMICALS, INCORPORATED (JP) | 2021-03-16 | — | — | US | disclosed |
| US-20190284364-A1 | FILLER FOR TIRES, RUBBER COMPOSITION FOR TIRES, TIRE, METHOD FOR PRODUCING FILLER FOR TIRES, AND AGGREGATION INHIBITOR | HARIMA CHEMICALS, INCORPORATED (JP) | 2019-09-19 | — | — | US | disclosed |
| EP-3459997-A1 | FILLER FOR TIRES, RUBBER COMPOSITION FOR TIRES, TIRE, METHOD FOR PRODUCING FILLER FOR TIRES, AND AGGREGATION INHIBITOR | Harima Chemicals, Incorporated (JP) | 2019-03-27 | — | — | EP | disclosed |
| US-20100105805-A1 | PROCESS FOR PRODUCING RUBBER COMPOSITION FOR TIRE TREAD | BRIDGESTONE CORPORATION (JP) | 2010-04-29 | — | — | US | disclosed |
| EP-2128186-A1 | PROCESS FOR PRODUCING RUBBER COMPOSITION FOR TIRE TREAD | Bridgestone Corporation (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-20080058235-A1 | Lubricative Composition for Industrial Machinery and Equipment | NIPPON OIL CORPORATION (JP) | 2008-03-06 | — | — | US | disclosed |
| EP-0945488-B1 | Rubber composition | BRIDGESTONE CORP (JP) | 2006-12-27 | — | — | EP | disclosed |
| EP-1734103-A1 | LUBRICATING OIL COMPOSITION FOR INDUSTRIAL MACHINERY AND EQUIPMENT | Nippon Oil Corporation (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-0846724-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6559209-B1 | Method of making a rubber composition which is improved in a dispersibility of silica into rubber, a heat generating property and an abrasion property. The rubber composition comprises 15 to 85 parts by weight of silica per 100 parts of | BRIDGESTONE CORPORATION (JP) | 2003-05-06 | — | — | US | disclosed |
| EP-0945488-A2 | Rubber composition | Bridgestone Corporation (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5939493-A | NATURAL RUBBER OR DIENE SYNTHETIC RUBBER, METAL DITHIOPHOSPHATE, TERTIARY AMINE; REINFORCING INORGANIC FILLER | BRIDGESTONE CORPORATION (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0864604-A2 | Rubber composition | Bridgestone Corporation (JP) | 1998-09-16 | — | — | EP | disclosed |
| EP-0846724-A2 | RUBBER COMPOSITION AND PNEUMATIC TIRE | Bridgestone Corporation (JP) | 1998-06-10 | — | — | EP | disclosed |