Phenyl Salicylate

Phenyl Salicylate

SCHEMBL3688802

O=C(Oc1ccccc1)c1ccccc1O.O=C(c1ccccc1)c1ccccc1O

nearest known ligand 0.80

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.80
HSD17B10 Q99714 3/20 0.80
ALOX15 P16050 1/20 0.80
LIG1 P18858 1/20 0.56
KDM4E B2RXH2 4/20 0.54
ALDH1A1 P00352 4/20 0.54
LMNA P02545 4/20 0.54
MAPT P10636 3/20 0.54
SLC6A2 P23975 2/20 0.54
PDE4A P27815 2/20 0.54
SLC6A3 Q01959 2/20 0.54
TP53 P04637 1/20 0.54
CYP3A4 P08684 1/20 0.54
ADORA3 P0DMS8 1/20 0.54
CHRM1 P11229 1/20 0.54
TBXA2R P21731 1/20 0.54
ADRA1A P35348 1/20 0.54
KDR P35968 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenyl Salicylate SCHEMBL28207812 0.95 HPGD (0.83) HPGDHSD17B10ALOX15LIG1KDM4E
SCHEMBL3243067 0.93 HPGD (0.69) HPGDHSD17B10ALOX15LIG1KDM4E
SCHEMBL563932 0.90 HPGD (0.74) HPGDHSD17B10ALOX15LIG1KDM4E
Phenyl Salicylate SCHEMBL2519840 0.89 HPGD (1.00) HPGDHSD17B10ALOX15KDM4EALDH1A1
Phenyl Salicylate SCHEMBL29625250 0.89 HPGD (1.00) HPGDHSD17B10ALOX15KDM4EALDH1A1
Phenyl Salicylate SCHEMBL24326 0.89 HPGD (1.00) HPGDHSD17B10ALOX15KDM4EALDH1A1
SCHEMBL12919760 0.89 HPGD (0.62) HPGDHSD17B10ALOX15LIG1KDM4E
Phenyl Salicylate SCHEMBL28206866 0.88 HPGD (0.83) HPGDHSD17B10ALOX15KDM4EALDH1A1
Phenyl Salicylate SCHEMBL14151784 0.88 HPGD (0.96) HPGDHSD17B10ALOX15KDM4EALDH1A1
Phenyl Salicylate SCHEMBL21519783 0.88 HPGD (0.96) HPGDHSD17B10ALOX15KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084226-B1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2013-02-27 EP claimed
US-7686997-B2 Comprising a combination of 10 to 80 weight percent of a polyester, 5 to 50 weight percent of a polycarbonate, and 10 to 90 weight percent of a polyester-polycarbonate copolymer; transparent polyester-polycarbonate blends with improved weatherability and/or chemical resistance. SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-30 US claimed
EP-2084226-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2009-08-05 EP claimed
WO-2008063722-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-29 WO claimed
US-20080119618-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-05-22 US claimed
US-4636431-A ULTRAVIOLET ABSORBER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-01-13 US disclosed