SCHEMBL3689064

SCHEMBL3689064

C#Cc1ccc2cc3c([Si](C)(C)C)c4cc5ccccc5cc4c([Si](C)(C)C)c3cc2c1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 3/20 0.42
CYP1A1 P04798 2/20 0.42
CYP1A2 P05177 1/20 0.37
TYMS P04818 1/20 0.35
EGFR P00533 1/20 0.32
PDGFRB P09619 1/20 0.32
KDR P35968 1/20 0.32
ELANE P08246 2/20 0.32
NQO1 P15559 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PARP1 P09874 1/20 0.31
CYP2A6 P11509 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PYCR1 P32322 1/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648766 0.84 CYP1A1 (0.40) CYP1B1CYP1A1CYP1A2TYMSNQO1
SCHEMBL2541426 0.84 CYP1A1 (0.40) CYP1B1CYP1A1CYP1A2TYMSELANE
SCHEMBL3465692 0.83 NQO1 (0.33) ELANENQO1ALDH1A1CA1CA2
SCHEMBL11126903 0.80 CYP1A1 (0.56) CYP1B1CYP1A1CYP1A2ALDH1A1HIF1A
SCHEMBL5478903 0.80 CYP1A1 (0.56) CYP1B1CYP1A1CYP1A2ALDH1A1HIF1A
SCHEMBL5668942 0.80 CYP1A1 (0.56) CYP1B1CYP1A1CYP1A2ALDH1A1HIF1A
SCHEMBL16151203 0.80 NQO1 (0.44) CYP1B1CYP1A2ELANENQO1ALDH1A1
SCHEMBL825806 0.78 CYP1A1 (0.58) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10
SCHEMBL30375647 0.78 CYP1A1 (0.58) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10
SCHEMBL29750775 0.78 CYP1A1 (0.58) CYP1B1CYP1A1CYP1A2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1687830-B1 ORGANIC SEMICONDUCTING LAYER FORMULATIONS COMPRISING POLYACENES AND ORGANIC BINDER POLYMERS MERCK PATENT GMBH (DE) 2010-07-28 EP disclosed
EP-1808866-A1 Organic semiconducting layer formulations comprising polyacenes and organic binder polymers Merck Patent GmbH (DE) 2007-07-18 EP disclosed
EP-1783781-A2 ORGANIC SEMICONDUCTING LAYER FORMULATIONS COMPRISING POLYACENES AND ORGANIC BINDER POLYMERS Merck Patent GmbH (DE) 2007-05-09 EP disclosed