SCHEMBL3689417

SCHEMBL3689417

O=S(OCc1ccccc1)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
EPHX2 P34913 1/20 0.35
IDO1 P14902 1/20 0.35
AGXT P21549 1/20 0.34
ALDH1A1 P00352 3/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MAPK1 P28482 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A3 Q01959 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
PDPK1 O15530 1/20 0.33
MTOR P42345 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776935 0.79 TSHR (0.52) TSHREPHX2IDO1AGXTALDH1A1
SCHEMBL28652165 0.78 TSHR (0.43) TSHREPHX2IDO1AGXTALDH1A1
SCHEMBL776867 0.75 NR4A2 (0.43) EPHX2IDO1AGXTKMT2ALMNA
SCHEMBL779903 0.72 CA12 (0.35) ALDH1A1CA1CA2CA9GAA
SCHEMBL4344980 0.72 TSHR (0.44) TSHREPHX2IDO1AGXTALDH1A1
SCHEMBL10692407 0.72 TSHR (0.44) TSHREPHX2IDO1AGXTALDH1A1
SCHEMBL779894 0.71 NR4A2 (0.49) IDO1AGXT
SCHEMBL4342737 0.71 TSHR (0.43) TSHREPHX2IDO1AGXTALDH1A1
SCHEMBL778273 0.70 CA1 (0.32) CA1CA2CA9
SCHEMBL7698932 0.68 TSHR (0.41) TSHREPHX2IDO1AGXTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7794876-B2 Pentafluorophenyloxy compound, and nonaqueous electrolyte solution and lithium secondary battery using same UBE INDUSTRIES, LTD. (JP) 2010-09-14 US disclosed
US-20080107969-A1 Pentafluorophenyl Methyl Oxalate; good electrical, cycling and storage properties; reacting pentafluorophenol with ethyl chloroglyoxylate UBE INDUSTRIES, LTD. (JP) 2008-05-08 US disclosed