Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369919 | 0.88 | GRM4 (0.78) | GRM4KCNH2 | |
| SCHEMBL370495 | 0.83 | GRM4 (1.00) | GRM4KCNH2 | |
| SCHEMBL369389 | 0.82 | GRM4 (1.00) | GRM4KCNH2 | |
| SCHEMBL370952 | 0.81 | GRM4 (0.95) | GRM4KCNH2 | |
| SCHEMBL366948 | 0.81 | GRM4 (0.70) | GRM4KCNH2 | |
| SCHEMBL369330 | 0.80 | GRM4 (1.00) | GRM4KCNH2 | |
| SCHEMBL370776 | 0.80 | GRM4 (0.69) | GRM4KCNH2 | |
| SCHEMBL369715 | 0.79 | GRM4 (1.00) | GRM4KCNH2 | |
| SCHEMBL370125 | 0.78 | GRM4 (0.96) | GRM4KCNH2 | |
| SCHEMBL370780 | 0.77 | GRM4 (0.71) | GRM4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593277-A2 | NOVEL FUSED PYRAZOLE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX Pharma S.A. (CH) | 2013-05-22 | — | — | EP | claimed |
| WO-2012009000-A2 | NOVEL FUSED PYRAZOLE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA S.A. (CH) | 2012-01-19 | — | — | WO | claimed |