Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 10/20 | 0.41 |
| ▸ | MC1R | Q01726 | 9/20 | 0.41 |
| ▸ | MC5R | P33032 | 8/20 | 0.41 |
| ▸ | MC3R | P41968 | 8/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1324264 | 0.89 | MC1R (0.47) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL1324267 | 0.89 | MC1R (0.47) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL1308385 | 0.89 | MC4R (0.43) | MC4RMC1RMC5RMC3R | |
| SCHEMBL1308389 | 0.89 | MC4R (0.43) | MC4RMC1RMC5RMC3R | |
| SCHEMBL1325265 | 0.89 | MC4R (0.44) | MC4RMC1RMC5RMC3R | |
| SCHEMBL1325267 | 0.89 | MC4R (0.44) | MC4RMC1RMC5RMC3R | |
| SCHEMBL1307814 | 0.88 | MC4R (0.43) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL1307815 | 0.88 | MC4R (0.43) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL1310141 | 0.88 | MC4R (0.43) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL2315290 | 0.88 | MC4R (0.43) | MC4RMC1RMC5RMC3RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010052256-A1 | MELANOCORTIN RECEPTOR ANTAGONIST COMPOUNDS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | claimed |