Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516917 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL3690143 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL8516915 | 1.00 | TSHR (0.46) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL27356316 | 0.97 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2899549 | 0.89 | — | — | |
| SCHEMBL2899543 | 0.89 | — | — | |
| SCHEMBL6127512 | 0.80 | TSHR (0.58) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL11288759 | 0.80 | TSHR (0.58) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL6899958 | 0.79 | TSHR (0.54) | TSHRFAAHTRPV1ALDH1A1FASN | |
| SCHEMBL15641831 | 0.79 | TSHR (0.54) | TSHRFAAHTRPV1ALDH1A1FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190893-A1 | METHOD FOR PRODUCING SILANE-MODIFIED COPOLYMERS | Construction Research and Technology GmbH (DE) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009033974-A1 | METHOD FOR PRODUCING SILANE-MODIFIED COPOLYMERS | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |