Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690260 | 1.00 | AAK1 (0.46) | AAK1IDO1TSHRCTSSCTSK | |
| SCHEMBL2129097 | 0.91 | AAK1 (0.46) | AAK1IDO1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL2129061 | 0.85 | AAK1 (0.47) | AAK1IDO1TSHR | |
| SCHEMBL2129066 | 0.85 | AAK1 (0.47) | AAK1IDO1TSHR | |
| SCHEMBL3691588 | 0.84 | AAK1 (0.43) | AAK1IDO1TSHRCTSSCTSK | |
| SCHEMBL3691586 | 0.84 | AAK1 (0.43) | AAK1IDO1TSHRCTSSCTSK | |
| SCHEMBL589720 | 0.84 | AAK1 (0.46) | AAK1IDO1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL3693377 | 0.83 | AAK1 (0.42) | AAK1IDO1TSHRCTSSCTSK | |
| SCHEMBL3693374 | 0.83 | AAK1 (0.42) | AAK1IDO1TSHRCTSSCTSK | |
| SCHEMBL3694054 | 0.82 | AAK1 (0.41) | AAK1IDO1TSHRCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2452944-A1 | DIPHENYL SULFIDE DERIVATIVES AND MEDICINES CONTAINING SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2012-05-16 | — | — | EP | disclosed |