Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369038 | 1.00 | SCN9A (0.77) | SCN9A | |
| SCHEMBL368401 | 0.88 | SCN9A (0.81) | SCN9A | |
| SCHEMBL368520 | 0.88 | SCN9A (0.81) | SCN9A | |
| SCHEMBL368402 | 0.88 | SCN9A (0.81) | SCN9A | |
| SCHEMBL15383822 | 0.88 | SCN9A (0.57) | SCN9A | |
| SCHEMBL787721 | 0.87 | SCN9A (1.00) | SCN9A | |
| SCHEMBL787722 | 0.87 | SCN9A (1.00) | SCN9A | |
| SCHEMBL793340 | 0.87 | SCN9A (1.00) | SCN9A | |
| SCHEMBL364424 | 0.82 | SCN9A (0.59) | SCN9A | |
| SCHEMBL17049435 | 0.81 | SCN9A (0.88) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593434-A1 | PYRIDINE COMPOUNDS AS SODIUM CHANNEL BLOCKERS | Purdue Pharma LP (US) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007836-A1 | PYRIDINE COMPOUNDS AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA .LP. (US) | 2012-01-19 | — | — | WO | disclosed |