SCHEMBL369050

SCHEMBL369050

C=C[CH]NC(=N)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL596395 0.75
Hydrochloric Acid SCHEMBL938893 0.73
SCHEMBL1065229 0.71
SCHEMBL3854305 0.71
SCHEMBL17022788 0.69
SCHEMBL5969607 0.67 TSHR (0.30)
SCHEMBL8192999 0.65
SCHEMBL15946378 0.65
SCHEMBL77747 0.63
SCHEMBL677877 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150150985-A1 SOLID PHARMACEUTICAL FORMULATION WITH DELAYED RELEASE BAYER ANIMAL HEALTH GMBH (DE) 2015-06-04 US claimed
US-8569313-B2 Meta-substituted phenyl sulfonyl amides of secondary amino acid amides, the production thereof, and use thereof as matriptase inhibitors THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) 2013-10-29 US claimed
US-20100305090-A1 META-SUBSTITUTED PHENYL SULFONYL AMIDES OF SECONDARY AMINO ACID AMIDES, THE PRODUCTION THEREOF, AND USE THEREOF AS MATRIPTASE INHIBITORS THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) 2010-12-02 US claimed
US-20100210552-A1 HUMAN GLUCAGON-LIKE PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2010-08-19 US claimed
JP-2009532484-A 2009-09-10 JP claimed
EP-2013167-A2 TOTAL SYNTHESIS OF SALINOSPORAMIDE A AND ANALOGS THEREOF Nereus Pharmaceuticals, Inc. (US) 2009-01-14 EP claimed
US-20070287670-A1 HUMAN GLUCAGON-LIKE PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-12-13 US claimed
WO-2007117591-A2 TOTAL SYNTHESIS OF SALINOSPORAMIDE A AND ANALOGS THEREOF NEREUS PHARMACEUTICALS, INC. (US) 2007-10-18 WO claimed
EP-1572892-A4 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL MYERS SQUIBB CO (US) 2007-08-22 EP claimed
EP-1615653-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS Bristol-Myers Squibb Company (US) 2006-01-18 EP claimed
EP-0418696-A2 Derivatives of aminoacids MERCK PATENT GmbH (DE) 1991-03-27 EP claimed
EP-0371390-A2 Amino acid derivatives MERCK PATENT GmbH (DE) 1990-06-06 EP claimed
EP-0342325-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1989-11-23 EP claimed
CN-1037155-A Amino acid derivative MERCK PATENT GMBH (DE) 1989-11-15 CN claimed
EP-0339483-A2 Renin inhbiting amino-acid derivatives MERCK PATENT GmbH (DE) 1989-11-02 EP claimed
EP-0337334-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1989-10-18 EP claimed
EP-0330925-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1989-09-06 EP claimed
EP-0328978-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1989-08-23 EP claimed
US-4714757-A ANALGESICS E. R. SQUIBB & SONS, INC. (US) 1987-12-22 US claimed
US-4558034-A Inhibitors of bacterial collagenase THE BOARD OF TRUSTEES OF THE UNIVERSITY OF KENTUCKY (US) 1985-12-10 US claimed