⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220014 | 0.97 | — | — | |
| SCHEMBL4087711 | 0.85 | — | — | |
| SCHEMBL3875964 | 0.83 | LPAR3 (0.54) | — | |
| SCHEMBL27861315 | 0.81 | LPAR3 (0.58) | — | |
| SCHEMBL28312728 | 0.81 | LPAR3 (0.58) | — | |
| SCHEMBL27815418 | 0.81 | LPAR3 (0.58) | — | |
| SCHEMBL28776038 | 0.81 | LPAR3 (0.58) | — | |
| SCHEMBL7229 | 0.78 | PPARD (0.48) | — | |
| SCHEMBL242136 | 0.78 | — | — | |
| SCHEMBL27444378 | 0.77 | PPARD (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817316-A1 | SULFINYLBENZYL AND THIOBENZYL DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2014-12-31 | — | — | EP | claimed |
| WO-2014093253-A1 | NOVEL AROMATIC THIO COMPOUNDS AS RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2014-06-19 | — | — | WO | claimed |
| WO-2013126438-A1 | SULFINYLBENZYL AND THIOBENZYL DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2013-08-29 | — | — | WO | claimed |
| WO-2015023837-A1 | ARYL DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS | ALLERGAN, INC. (US) | 2015-02-19 | — | — | WO | disclosed |
| US-20150045328-A1 | DISUBSTITUTED ARYL OXY DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS | ALLERGAN, INC. | 2015-02-12 | — | — | US | disclosed |
| US-8828973-B2 | Compounds as receptor modulators with therapeutic utility | ALLERGAN, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| WO-2014130572-A1 | SUBSTITUTED 6-METHOXY-4-AMINO-N-PHENYL-2-NAPHTAMIDES AS SPHINGOSINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2014-08-28 | — | — | WO | disclosed |
| US-20140221317-A1 | NOVEL COMPOUNDS AS RECEPTOR MODULATORS WITH THERAPEUTIC UTILITY | ALLERGAN, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8729110-B1 | 2-thio-1,3,4-oxadiazoles derivatives as sphingosine-1 phosphate receptors modulators | ALLERGAN, INC. (US) | 2014-05-20 | — | — | US | disclosed |
| US-8722712-B2 | Substituted aryl 1 ,2,4-oxadiazoles derivatives as sphingosine-1 phosphate receptors modulators | ALLERGAN, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| CN-101863794-B | 3' -alkoxy spirocyclic tetramic and tetronic acids | BAYER CROPSCIENCE AG | 2013-07-24 | — | — | CN | disclosed |
| EP-1190007-A2 | REACTIVE ADHESIVES AND COATINGS WITH TRIFUNCTIONAL OLEFINIC MONOMERS | Lord Corporation (US) | 2002-03-27 | — | — | EP | disclosed |
| EP-1185692-A1 | MONOLAYER AND ELECTRODE FOR DETECTING A LABEL-BEARING TARGET AND METHOD OF USE THEREOF | The University of North Carolina at Chapel Hill (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-1169329-A1 | OLIGONUCLEOTIDES HAVING ALKYLPHOSPHONATE LINKAGES AND METHODS FOR THEIR PREPARATION | ISIS PHARMACEUTICALS, INC. (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000077079-A2 | REACTIVE ADHESIVES AND COATINGS WITH TRIFUNCTIONAL OLEFINIC MONOMERS | LORD CORPORATION (US) | 2000-12-21 | — | — | WO | disclosed |
| WO-2000065099-A1 | MONOLAYER AND ELECTRODE FOR DETECTING A LABEL-BEARING TARGET AND METHOD OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-11-02 | — | — | WO | disclosed |
| US-6127127-A | Monolayer and electrode for detecting a label-bearing target and method of use thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-10-03 | — | — | US | disclosed |
| WO-2000049032-A1 | OLIGONUCLEOTIDES HAVING ALKYLPHOSPHONATE LINKAGES AND METHODS FOR THEIR PREPARATION | ISIS PHARMACEUTICALS, INC. (US) | 2000-08-24 | — | — | WO | disclosed |
| EP-0951517-A1 | ADDITIVES FOR CONTROLLING CURE RATE OF POLYMERIZABLE COMPOSITION | Lord Corporation (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998030645-A1 | ADDITIVES FOR CONTROLLING CURE RATE OF POLYMERIZABLE COMPOSITION | LORD CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |