SCHEMBL3693189

SCHEMBL3693189

Cc1cc(-c2cc(C)c(N=CCc3ccccn3)c(C)c2)cc(C)c1N=CCc1ccccn1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 4/20 0.40
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
NPC1 O15118 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
GRIN1 Q05586 1/20 0.36
KCNH2 Q12809 1/20 0.36
GRIN2B Q13224 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
HRH1 P35367 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL3697770 0.97 BRD4 (0.39) BRD4KDM4ECYP1A2CYP2C9CYP2C19
Bromide SCHEMBL3695596 0.97 BRD4 (0.39) BRD4KDM4ECYP1A2CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL3692252 0.97 BRD4 (0.39) BRD4KDM4ECYP1A2CYP2C9CYP2C19
Bromide SCHEMBL3698848 0.97 BRD4 (0.39) BRD4KDM4ECYP1A2CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL3691223 0.97 BRD4 (0.39) BRD4KDM4ECYP1A2CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL3691385 0.97 BRD4 (0.39) BRD4KDM4ECYP1A2CYP2C9CYP2C19
SCHEMBL6236001 0.88 SCN8A (0.40) BRD4KDM4EHRH3L3MBTL1HRH1
SCHEMBL5571424 0.85 ESR1 (0.35) BRD4KDM4EMAPTMEN1KMT2A
SCHEMBL5571603 0.85 CYP1A2 (0.40) BRD4KDM4ECYP1A2CYP2C9CYP2C19
SCHEMBL3693124 0.84 HRH3 (0.40) MAPTMEN1KMT2AHRH3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741240-B2 Transition metal compounds for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US disclosed
US-20080033125-A1 Transition Metal Compounds for Olefin Polymerization and Oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2008-02-07 US disclosed