Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 9/20 | 0.38 |
| ▸ | MC1R | Q01726 | 8/20 | 0.38 |
| ▸ | MC5R | P33032 | 5/20 | 0.38 |
| ▸ | MC3R | P41968 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309192 | 0.93 | MC4R (0.41) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL1309066 | 0.90 | MC4R (0.41) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL1325428 | 0.90 | MC4R (0.40) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL1311203 | 0.90 | MC4R (0.41) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL1308853 | 0.89 | MC4R (0.42) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL3696936 | 0.89 | MC4R (0.40) | MC4RMC1RMC5RMC3RKMT2A | |
| SCHEMBL3686987 | 0.89 | MC4R (0.39) | MC4RMC1RMC5RMC3R | |
| SCHEMBL1325224 | 0.88 | MC4R (0.40) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL15703970 | 0.87 | MC4R (0.40) | MC4RMC1RMC5RMC3RALDH1A1 | |
| SCHEMBL15704112 | 0.87 | MC4R (0.39) | MC4RMC1RMC5RMC3RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010052255-A1 | MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | claimed |
| WO-2010052255-A1 | MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |