SCHEMBL3694948

SCHEMBL3694948

Nc1ccc(/N=N/c2ccc(/N=N/c3ccc(/N=N/c4ccc(N)c5ccccc45)cc3)cc2)c2ccccc12

nearest known ligand 0.89

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.89
KMT2A Q03164 5/20 0.89
MAPK1 P28482 5/20 0.89
TDP1 Q9NUW8 5/20 0.89
NPC1 O15118 4/20 0.89
L3MBTL1 Q9Y468 4/20 0.89
MAPT P10636 3/20 0.89
GLO1 Q04760 2/20 0.58
SENP3 Q9H4L4 3/20 0.56
SENP2 Q9HC62 3/20 0.56
SENP1 Q9P0U3 3/20 0.56
SUMO2 P61956 2/20 0.56
SUMO1 P63165 2/20 0.56
SENP7 Q9BQF6 2/20 0.56
INSR P06213 1/20 0.51
SLC7A11 Q9UPY5 1/20 0.49
CYP3A4 P08684 4/20 0.47
TSHR P16473 3/20 0.47
TP53 P04637 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3694949 1.00 MEN1 (0.89) MEN1KMT2AMAPK1TDP1NPC1
SCHEMBL3694952 1.00 MEN1 (0.89) MEN1KMT2AMAPK1TDP1NPC1
SCHEMBL30393456 0.96 MEN1 (0.96) MEN1KMT2AMAPK1TDP1NPC1
SCHEMBL10661556 0.94 MEN1 (0.79) MEN1KMT2AMAPK1TDP1NPC1
SCHEMBL29373288 0.94 MEN1 (0.79) MEN1KMT2AMAPK1TDP1NPC1
SCHEMBL18872626 0.94 MEN1 (0.79) MEN1KMT2AMAPK1TDP1NPC1
SCHEMBL15274139 0.94 MEN1 (1.00) MEN1KMT2AMAPK1TDP1NPC1
SCHEMBL243333 0.94 MEN1 (1.00) MEN1KMT2AMAPK1TDP1NPC1
SCHEMBL31073963 0.94 MEN1 (1.00) MEN1KMT2AMAPK1TDP1NPC1
SCHEMBL243332 0.94 MEN1 (1.00) MEN1KMT2AMAPK1TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754295-B2 Single substrate guest-host polymer dispersed liquid crystal displays INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-07-13 US disclosed
WO-2008005202-A2 SINGLE SUBSTRATE GUEST-HOST POLYMER LIQUID CRYSTAL DISPLAYS INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-01-10 WO disclosed
US-20080003379-A1 electronically modulated imaging layer comprises a dichroic or pleochroic dye in a fixed latex polymer matrix; low cost; display having excellent brightness, high contrast, and low switching voltage EASTMAN KODAK COMPANY 2008-01-03 US disclosed
US-4122027-A CONTRAST RATIOS GENERAL ELECTRIC COMPANY (US) 1978-10-24 US disclosed