Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5091166 | 0.97 | FFAR3 (0.38) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27533512 | 0.94 | FFAR3 (0.39) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL66882 | 0.71 | — | — | |
| Succinic Acid SCHEMBL30712481 | 0.71 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL22471655 | 0.71 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL1335834 | 0.71 | FFAR3 (0.56) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL165196 | 0.71 | — | — | |
| Succinic Acid SCHEMBL156757 | 0.71 | — | — | |
| SCHEMBL5796976 | 0.71 | — | — | |
| SCHEMBL6725185 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456254-B1 | SUPPORTED TITANIUM-CONTAINING CATALYST FOR HOMO-, CO-, AND TER-POLYMERIZATION OF OLEFINS | POLIMERI EUROPA SPA (IT) | 2010-03-24 | — | — | EP | disclosed |
| US-7449528-B2 | Supported catalyst containing active titanium in the homo, co-, and ter-polymerization of olefin-unsaturated compounds | POLIMERI EUROPA S.P.A. (IT) | 2008-11-11 | — | — | US | disclosed |