⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865292 | 0.77 | — | — | |
| SCHEMBL13408201 | 0.77 | KAT2B (0.30) | — | |
| SCHEMBL13408412 | 0.77 | KAT2B (0.30) | — | |
| SCHEMBL27764215 | 0.76 | — | — | |
| SCHEMBL28176953 | 0.76 | — | — | |
| SCHEMBL27764189 | 0.76 | — | — | |
| SCHEMBL27764190 | 0.76 | — | — | |
| SCHEMBL2089866 | 0.70 | — | — | |
| SCHEMBL31029450 | 0.70 | — | — | |
| SCHEMBL25813854 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101600681-B | Process for the reductive amination of aldehydes and ketones | DOW GLOBAL TECHNOLOGIES INC | 2013-09-18 | — | — | CN | claimed |
| EP-2121570-B1 | PROCESS FOR THE REDUCTIVE AMINATION OF ALDEHYDES AND KETONES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-09-03 | — | — | EP | disclosed |
| US-8586793-B2 | Process for the reductive amination of aldehydes and ketones via the formation of macrocyclic polyimine intermediates | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-11-19 | — | — | US | disclosed |
| CN-101600681-B | Process for the reductive amination of aldehydes and ketones | DOW GLOBAL TECHNOLOGIES INC | 2013-09-18 | — | — | CN | disclosed |
| CN-101213167-B | Process for reductive amination of aldehydes and ketones by formation of macrocyclic polyimine intermediates | DOW GLOBAL TECHNOLOGIES INC | 2012-05-23 | — | — | CN | disclosed |
| US-20100222611-A1 | Process for the Reductive Amination of Aldehydes and Ketones Via the Formation of Macrocyclic Polyimine Intermediates | DOW GLOBAL TECHNOLOGIES LLC | 2010-09-02 | — | — | US | disclosed |
| CN-101600681-A | The reduction amination method of aldehyde and ketone | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-12-09 | — | — | CN | disclosed |
| EP-2121570-A1 | PROCESS FOR THE REDUCTIVE AMINATION OF ALDEHYDES AND KETONES | Dow Global Technologies Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-1902011-B1 | PROCESS FOR THE REDUCTIVE AMINATION OF ALDEHYDES AND KETONES VIA THE FORMATION OF MACROCYCLIC POLYIMINE INTERMEDIATES | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20080167499-A1 | PROCESS FOR THE REDUCTIVE AMINATION OF ALDEHYDES AND KETONES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-07-10 | — | — | US | disclosed |
| CN-101213167-A | Process for reductive amination of aldehydes and ketones by formation of macrocyclic polyimine intermediates | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-07-02 | — | — | CN | disclosed |
| WO-2008076795-A1 | PROCESS FOR THE REDUCTIVE AMINATION OF ALDEHYDES AND KETONES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| EP-1902011-A2 | PROCESS FOR THE REDUCTIVE AMINATION OF ALDEHYDES AND KETONES VIA THE FORMATION OF MACROCYCLIC POLYIMINE INTERMEDIATES | Dow Gloval Technologies Inc. (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007005594-A2 | PROCESS FOR THE REDUCTIVE AMINATION OF ALDEHYDES AND KETONES VIA THE FORMATION OF MACROCYCLIC POLYIMINE INTERMEDIATES | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2007-01-11 | — | — | WO | disclosed |