⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2646374 | 1.00 | — | — | |
| SCHEMBL5053538 | 1.00 | — | — | |
| SCHEMBL2647260 | 1.00 | — | — | |
| SCHEMBL25752112 | 1.00 | — | — | |
| SCHEMBL9873821 | 1.00 | — | — | |
| SCHEMBL25446671 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL31707162 | 0.98 | SLC6A2 (0.39) | — | |
| SCHEMBL1225118 | 0.94 | SLC6A2 (0.46) | — | |
| SCHEMBL13510425 | 0.94 | SLC6A2 (0.46) | — | |
| SCHEMBL3478050 | 0.94 | SLC6A2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3710439-A1 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2020-09-23 | — | — | EP | disclosed |
| EP-2460814-A1 | PEPTIDIC COMPOUND AND USE OF SAME | Keio University (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-20120122797-A1 | PEPTIDIC COMPOUND AND USE OF SAME | KEIO UNIVERSITY (JP) | 2012-05-17 | — | — | US | disclosed |
| US-20120122797-A1 | PEPTIDIC COMPOUND AND USE OF SAME | KEIO UNIVERSITY (JP) | 2012-05-17 | — | — | US | disclosed |
| EP-1838712-A1 | PYRAZOLOPYRIMIDINE COMPOUNDS AS ANTITUMOR AGENTS | AstraZeneca AB (SE) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006064196-A1 | PYRAZOLOPYRIMIDINE COMPOUNDS AS ANTITUMOR AGENTS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |
| US-5051444-A | Pyrrolidine derivatives as anti-amnesia agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4880827-A | Pyrrolidine derivatives having inhibitory action for proline specific endopepidase | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| EP-0238319-A1 | Pyrrolidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-09-23 | — | — | EP | disclosed |