Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956395 | 0.92 | ALK (0.47) | ALKTTK | |
| SCHEMBL3702747 | 0.90 | TTK (0.52) | ALKTTK | |
| SCHEMBL2949077 | 0.88 | TTK (0.48) | TTK | |
| SCHEMBL3699208 | 0.87 | TTK (0.47) | ALKTTK | |
| SCHEMBL2953043 | 0.84 | TTK (0.54) | ALKTTK | |
| SCHEMBL3024756 | 0.83 | TTK (0.44) | TTK | |
| SCHEMBL2955059 | 0.83 | TTK (0.48) | TTK | |
| SCHEMBL2953124 | 0.83 | TTK (0.51) | ALKTTK | |
| SCHEMBL3704347 | 0.82 | TTK (0.52) | ALKTTK | |
| SCHEMBL3711875 | 0.82 | TTK (0.53) | ALKTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122840-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYREXIS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122840-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VHL, TP53, ASAH2 | ALK 2060/4885TTK 4589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.