Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 5/20 | 0.61 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694985 | 0.89 | IAPP (0.64) | IAPPBIDMCL1BCL2L1BAK1 | |
| SCHEMBL3691581 | 0.84 | IAPP (0.58) | IAPPHPGDMAPT | |
| SCHEMBL3691344 | 0.84 | IAPP (0.48) | IAPPLTB4RLTB4R2PPARA | |
| SCHEMBL3686569 | 0.81 | IAPP (0.57) | IAPP | |
| SCHEMBL8005173 | 0.76 | IAPP (0.75) | IAPPBIDMCL1BCL2L1BAK1 | |
| SCHEMBL3699529 | 0.74 | IAPP (0.48) | IAPPHPGDPPARA | |
| SCHEMBL6957846 | 0.71 | HPGD (0.60) | IAPPHPGDLMNAHTR7 | |
| SCHEMBL27864721 | 0.70 | AR (0.43) | HPGDBCL2L1LMNAMAPTHIF1A | |
| SCHEMBL982273 | 0.70 | ELANE (0.45) | IAPPBIDMCL1BCL2L1BAK1 | |
| SCHEMBL29138358 | 0.68 | ELANE (0.46) | IAPPBIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227449-A1 | NOVEL BETA-HYDROXYKETONES AND BETA-ALKOXYKETONES WITH ESTROGENIC ACTIVITY | Pulkkinen, Juha (FI) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009066008-A1 | NOVEL BETA-HYDROXYKETONES AND BETA-ALKOXYKETONES WITH ESTROGENIC ACTIVITY | PULKKINEN JUHA (FI) | 2009-05-28 | — | — | WO | disclosed |