Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.72 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.37 |
| ▸ | CCR9 | P51686 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362396 | 1.00 | GPBAR1 (0.72) | GPBAR1PROKR1KDM4CKDM5BKDM4E | |
| SCHEMBL369904 | 1.00 | GPBAR1 (0.72) | GPBAR1PROKR1KDM4CKDM5BKDM4E | |
| SCHEMBL1389772 | 0.97 | GPBAR1 (0.78) | GPBAR1PROKR1KDM4CKDM5BKDM4E | |
| SCHEMBL364688 | 0.97 | GPBAR1 (0.78) | GPBAR1PROKR1KDM4CKDM5BKDM4E | |
| SCHEMBL370854 | 0.97 | GPBAR1 (0.78) | GPBAR1PROKR1KDM4CKDM5BKDM4E | |
| SCHEMBL370856 | 0.97 | GPBAR1 (0.78) | GPBAR1PROKR1KDM4CKDM5BKDM4E | |
| SCHEMBL363135 | 0.97 | GPBAR1 (0.78) | GPBAR1PROKR1KDM4CKDM5BKDM4E | |
| SCHEMBL1389975 | 0.97 | GPBAR1 (0.78) | GPBAR1PROKR1KDM4CKDM5BKDM4E | |
| SCHEMBL363114 | 0.97 | GPBAR1 (0.78) | GPBAR1PROKR1KDM4CKDM5BKDM4E | |
| SCHEMBL10290855 | 0.91 | GPBAR1 (0.59) | GPBAR1PROKR1KDM4CKDM5BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |