Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10316830 | 0.80 | HTR1D (0.42) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL10316812 | 0.78 | HTR1D (0.40) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL10317008 | 0.78 | BCHE (0.41) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL10317160 | 0.76 | CD274 (0.39) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL3700522 | 0.74 | CMA1 (0.58) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL10317183 | 0.74 | MEN1 (0.36) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL436837 | 0.74 | DRD4 (0.44) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL1083649 | 0.69 | CMA1 (0.56) | MEN1KMT2ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL1048549 | 0.68 | CMA1 (0.69) | POLBPLAU | |
| SCHEMBL3704000 | 0.68 | MAPT (0.44) | ALDH1A1HPGDSMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2211867-A1 | PROCESS FOR SYNTHESIZING PHOSPHONIC AND PHOSPHINIC ACID COMPOUNDS | Janssen Pharmaceutica N.V. (BE) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009051746-A1 | PROCESS FOR SYNTHESIZING PHOSPHONIC AND PHOSPHINIC ACID COMPOUNDS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-04-23 | — | — | WO | disclosed |