Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 17/20 | 0.67 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.67 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.67 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290240 | 0.91 | LPAR1 (0.76) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL2289326 | 0.91 | LPAR1 (0.76) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL343414 | 0.91 | LPAR1 (0.76) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL3713320 | 0.90 | LPAR1 (0.67) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL14711762 | 0.89 | LPAR1 (0.67) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL2294095 | 0.89 | LPAR1 (0.69) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL14788667 | 0.89 | LPAR1 (0.64) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL2289205 | 0.86 | LPAR1 (0.66) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL3710129 | 0.86 | LPAR1 (0.87) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL2289210 | 0.86 | LPAR1 (0.62) | LPAR1LPAR3LPAR2ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150028265-A1 | CONJUGATED POLYMERS FOR ELECTRONIC DEVICES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-01-29 | — | — | US | disclosed |
| US-20110301142-A1 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. | 2011-12-08 | — | — | US | disclosed |
| US-20110301142-A1 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. | 2011-12-08 | — | — | US | disclosed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150028265-A1 | CONJUGATED POLYMERS FOR ELECTRONIC DEVICES | EED, EPCAM, GABRE | LPAR1 4392/4885LPAR3 4579/4885LPAR2 4461/4885 |
| US-20110301142-A1 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | LPAR1, LPAR2, LPAR4 | LPAR1 1/4885LPAR3 5/4885LPAR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.