Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.51 |
| ▸ | SCN7A | Q01118 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.51 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3065606 | 0.97 | SCN9A (0.49) | SCN9ASCN7AKCNH2SCN10ASCN5A | |
| Hydrochloric Acid SCHEMBL10180648 | 0.93 | SCN9A (0.51) | SCN9ASCN7AKCNH2SCN10ASCN5A | |
| SCHEMBL3069830 | 0.89 | SCN9A (0.47) | SCN9A | |
| Trifluoroacetic Acid SCHEMBL3061711 | 0.87 | SCN9A (0.41) | SCN9ASCN7AKCNH2SCN10ASCN5A | |
| SCHEMBL3051748 | 0.87 | SCN9A (0.53) | SCN9ASCN7AKCNH2SCN10ASCN5A | |
| SCHEMBL3064269 | 0.87 | STAT3 (0.52) | SCN9A | |
| SCHEMBL3050791 | 0.86 | SCN9A (0.51) | SCN9ASCN10A | |
| Hydrochloric Acid SCHEMBL3066788 | 0.86 | SCN9A (0.49) | SCN9ASCN7AKCNH2SCN10ASCN5A | |
| Hydrochloric Acid SCHEMBL3053398 | 0.84 | SCN9A (0.52) | SCN9ASCN7AKCNH2SCN10ASCN5A | |
| SCHEMBL3058988 | 0.83 | STAT3 (0.49) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009057811-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-05-07 | — | — | WO | disclosed |