⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL30662442 | 0.95 | — | — | |
| Acetonitrile SCHEMBL30662445 | 0.95 | — | — | |
| Acetonitrile SCHEMBL31357011 | 0.78 | — | — | |
| Acetonitrile SCHEMBL1594871 | 0.78 | — | — | |
| Acetonitrile SCHEMBL59423 | 0.78 | — | — | |
| Acetonitrile SCHEMBL4020626 | 0.70 | — | — | |
| Acetonitrile SCHEMBL1330624 | 0.68 | — | — | |
| Acetonitrile SCHEMBL10523138 | 0.68 | — | — | |
| Acetonitrile SCHEMBL6693864 | 0.68 | — | — | |
| Acetonitrile SCHEMBL1331294 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084839-A | Natural sesquiterpene compound with agricultural pathogenic bacteria resisting effect and preparation method and application thereof | 海南医学院 | 2024-05-28 | — | — | CN | claimed |
| CN-117164526-A | 2- (piperazine-2-yl) acetonitrile derivative, and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2023-12-05 | — | — | CN | claimed |
| US-12637461-B2 | Compounds for the activation of AMPK | PFIZER INC. (US) | 2026-05-26 | — | — | US | disclosed |
| US-12577240-B2 | Antiviral heteroaryl ketone derivatives | PFIZER INC. (US) | 2026-03-17 | — | — | US | disclosed |
| EP-4695226-A1 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF | Pfizer Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20250346567-A1 | SUBSTITUTED PYRIDINE AND PHENYL COMPOUNDS | PFIZER INC. (US) | 2025-11-13 | — | — | US | disclosed |
| US-12466803-B2 | BCKDK inhibitors and/or degraders | PFIZER INC. (US) | 2025-11-11 | — | — | US | disclosed |
| WO-2025224599-A1 | PYRROLIDINE-BASED GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| US-20250326741-A1 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER INC. (US) | 2025-10-23 | — | — | US | disclosed |
| EP-4634169-A1 | 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF | Pfizer Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4605076-A1 | PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 3 (PNPLA3) MODIFIERS | Pfizer Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| US-9902714-B2 | Quinoxaline derivatives useful as FGFR kinase modulators | ASTEX THERAPEUTICS LTD (GB) | 2018-02-27 | — | — | US | disclosed |
| US-20170101396-A1 | QUINOXALINE DERIVATIVES USEFUL AS FGFR KINASE MODULATORS | ASTEX THERAPEUTICS LTD (GB) | 2017-04-13 | — | — | US | disclosed |
| CN-106459010-A | Quinoxaline derivatives useful as FGFR kinase modulators | 阿斯特克斯治疗有限公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-3122742-A1 | QUINOXALINE DERIVATIVES USEFUL AS FGFR KINASE MODULATORS | Astex Therapeutics Ltd (GB) | 2017-02-01 | — | — | EP | disclosed |
| US-20160354483-A1 | COMPOUNDS, CONJUGATES AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-12-08 | — | — | US | disclosed |
| US-9353150-B2 | Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-05-31 | — | — | US | disclosed |
| WO-2015144803-A1 | QUINOXALINE DERIVATIVES USEFUL AS FGFR KINASE MODULATORS | ASTEX THERAPEUTICS LTD (GB) | 2015-10-01 | — | — | WO | disclosed |
| US-20140187500-A1 | COMPOUNDS, CONJUGATES AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2014-07-03 | — | — | US | disclosed |
| WO-2010002451-A1 | NAPHTHYRIDIN DERIVATIVES | CONCERT PHARMACEUTICALS, INC. (US) | 2010-01-07 | — | — | WO | disclosed |