Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL3705787 | 0.96 | CA4 (0.43) | CA4CA1FAHD1LMNACYP3A4 | |
| Lithium Ion SCHEMBL16030957 | 0.96 | — | — | |
| Potassium Ion SCHEMBL3702648 | 0.96 | CA4 (0.40) | CA4CA1FAHD1LMNACYP3A4 | |
| SCHEMBL16880025 | 0.92 | — | — | |
| SCHEMBL11293371 | 0.92 | — | — | |
| Potassium Ion SCHEMBL3290026 | 0.92 | CA4 (0.43) | CA4CA1FAHD1LMNACYP3A4 | |
| Zinc Ion SCHEMBL3704342 | 0.92 | — | — | |
| SCHEMBL3981033 | 0.92 | — | — | |
| SCHEMBL3708053 | 0.92 | CA4 (0.45) | CA4CA1FAHD1LMNACYP3A4 | |
| SCHEMBL10611391 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2952569-B1 | CALCIUM SEQUESTERING COMPOSITION | RIVERTOP RENEWABLES INC (US) | 2017-01-25 | — | — | EP | claimed |
| US-20160230123-A1 | CALCIUM SEQUESTERING COMPOSITION | RIVERTOP RENEWABLES INC (US) | 2016-08-11 | — | — | US | claimed |
| EP-2952569-A1 | CALCIUM SEQUESTERING COMPOSITION | Rivertop Renewables, Inc. (US) | 2015-12-09 | — | — | EP | claimed |
| EP-2699660-A1 | CALCIUM SEQUESTERING COMPOSITION | Rivertop Renewables, Inc. (US) | 2014-02-26 | — | — | EP | claimed |
| US-20120277141-A1 | CALCIUM SEQUESTERING COMPOSITION | SILICON VALLEY BANK | 2012-11-01 | — | — | US | claimed |
| WO-2012145688-A1 | CALCIUM SEQUESTERING COMPOSITION | RIVERTOP RENEWABLES, INC. (US) | 2012-10-26 | — | — | WO | claimed |
| US-9758462-B2 | Nitric acid oxidation processes | RIVERTOP RENEWABLES, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-9670124-B2 | Nitric acid oxidation process | RIVERTOP RENEWABLES, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| EP-2952569-B1 | CALCIUM SEQUESTERING COMPOSITION | RIVERTOP RENEWABLES INC (US) | 2017-01-25 | — | — | EP | disclosed |
| US-20160305028-A1 | CORROSION INHIBITING COMPOSITION | RIVERTOP RENEWABLES (US) | 2016-10-20 | — | — | US | disclosed |
| US-20160237016-A1 | OXIDATION PROCESS | RIVERTOP RENEWABLES INC (US) | 2016-08-18 | — | — | US | disclosed |
| US-20160230123-A1 | CALCIUM SEQUESTERING COMPOSITION | RIVERTOP RENEWABLES INC (US) | 2016-08-11 | — | — | US | disclosed |
| US-9404188-B2 | Corrosion inhibiting composition | RIVERTOP RENEWABLES (US) | 2016-08-02 | — | — | US | disclosed |
| EP-2638184-A1 | CORROSION INHIBITING COMPOSITION | Rivertop Renewables (US) | 2013-09-18 | — | — | EP | disclosed |
| US-20120295986-A1 | CALCIUM SEQUESTERING COMPOSITION | RIVERTOP RENEWABLES, INC. | 2012-11-22 | — | — | US | disclosed |
| US-20120277141-A1 | CALCIUM SEQUESTERING COMPOSITION | SILICON VALLEY BANK | 2012-11-01 | — | — | US | disclosed |
| WO-2012145688-A1 | CALCIUM SEQUESTERING COMPOSITION | RIVERTOP RENEWABLES, INC. (US) | 2012-10-26 | — | — | WO | disclosed |
| WO-2012145690-A1 | CALCIUM SEQUESTERING COMPOSITION | RIVERTOP RENEWABLES, INC. (US) | 2012-10-26 | — | — | WO | disclosed |
| WO-2012065001-A1 | CORROSION INHIBITING COMPOSITION | RIVERTOP RENEWABLES (US) | 2012-05-18 | — | — | WO | disclosed |
| US-20120119152-A1 | CORROSION INHIBITING COMPOSITION | SILICON VALLEY BANK | 2012-05-17 | — | — | US | disclosed |