Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370196 | 0.79 | GPBAR1 (0.42) | GPBAR1 | |
| SCHEMBL369994 | 0.76 | GPBAR1 (0.50) | GPBAR1 | |
| SCHEMBL369995 | 0.76 | GPBAR1 (0.50) | GPBAR1 | |
| SCHEMBL371379 | 0.66 | GPBAR1 (0.39) | GPBAR1 | |
| SCHEMBL364013 | 0.65 | GPBAR1 (0.56) | GPBAR1 | |
| SCHEMBL1390173 | 0.65 | GPBAR1 (0.56) | GPBAR1 | |
| SCHEMBL1390174 | 0.65 | GPBAR1 (0.56) | GPBAR1 | |
| SCHEMBL1389828 | 0.65 | GPBAR1 (0.53) | GPBAR1 | |
| SCHEMBL363939 | 0.65 | GPBAR1 (0.53) | GPBAR1 | |
| SCHEMBL1389826 | 0.65 | GPBAR1 (0.53) | GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |