Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263140 | 0.76 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1 | |
| SCHEMBL446002 | 0.66 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL1585986 | 0.63 | HSP90AA1 (0.73) | HSP90AA1HSP90AB1 | |
| SCHEMBL12368044 | 0.62 | HSP90AB1 (0.61) | HSP90AA1HSP90AB1 | |
| SCHEMBL1586249 | 0.62 | HSP90AA1 (0.76) | HSP90AA1HSP90AB1 | |
| SCHEMBL13950203 | 0.62 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1 | |
| SCHEMBL3703704 | 0.61 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL1586649 | 0.61 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1 | |
| SCHEMBL420150 | 0.60 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1 | |
| SCHEMBL30050709 | 0.60 | HSP90AA1 (0.74) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193135-A1 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | Synta Pharmaceuticals Corp. (US) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009023211-A1 | TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2009-02-19 | — | — | WO | disclosed |