Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3017083 | 0.98 | GCK (0.48) | GCK | |
| SCHEMBL3017123 | 0.98 | GCK (0.48) | GCK | |
| SCHEMBL1740046 | 0.86 | GCK (0.46) | GCK | |
| SCHEMBL1740043 | 0.86 | GCK (0.46) | GCK | |
| SCHEMBL3008569 | 0.84 | GCK (0.48) | GCK | |
| SCHEMBL1741312 | 0.83 | GCK (0.47) | GCK | |
| SCHEMBL1741313 | 0.83 | GCK (0.47) | GCK | |
| SCHEMBL1739761 | 0.80 | GCK (0.72) | GCK | |
| SCHEMBL1739758 | 0.80 | GCK (0.72) | GCK | |
| SCHEMBL1739976 | 0.79 | GCK (0.63) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010084428-A1 | SUBSTITUTED PYRAZINONE AMIDES | PFIZER INC. (US) | 2010-07-29 | — | — | WO | disclosed |