⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28782511 | 0.78 | — | — | |
| SCHEMBL9959990 | 0.72 | — | — | |
| SCHEMBL17766689 | 0.67 | — | — | |
| SCHEMBL2358757 | 0.67 | — | — | |
| SCHEMBL225420 | 0.65 | — | — | |
| SCHEMBL201126 | 0.64 | — | — | |
| SCHEMBL4514507 | 0.64 | CYP19A1 (0.31) | — | |
| SCHEMBL4499354 | 0.64 | — | — | |
| SCHEMBL25198260 | 0.59 | — | — | |
| SCHEMBL28909726 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114044769-B | Beta-indolyl quinazolinone derivative and preparation method and application thereof | 中山大学 | 2023-12-12 | — | — | CN | claimed |
| CN-114057760-B | Indoloquinazolinone spiro 1, 3-dioxolane compound, preparation method and application thereof | 成都大学 | 2023-10-20 | — | — | CN | claimed |
| CN-114057760-A | Indoloquinazolinone spiro 1, 3-dioxolane compound, preparation method and application thereof | 成都大学 | 2022-02-18 | — | — | CN | claimed |
| CN-114044769-A | Beta-indole quinazolinone derivative and preparation method and application thereof | 中山大学 | 2022-02-15 | — | — | CN | claimed |
| CN-121800787-A | Indoloquinazoline Synthesis method of ketone compound | 上海应用技术大学 | 2026-04-07 | — | — | CN | disclosed |
| CN-121015656-A | Application of indoloquinazolinone derivative in preparation of antitumor pharmaceutical composition | 广西科技大学 | 2025-11-28 | — | — | CN | disclosed |
| CN-121015656-A | Application of indoloquinazolinone derivative in preparation of antitumor pharmaceutical composition | 广西科技大学 | 2025-11-28 | — | — | CN | disclosed |
| CN-117924304-B | Chiral indolinone quinazolinone polycyclic compound containing dihydronaphthofuran structure, preparation method and application thereof | 成都大学 | 2025-09-16 | — | — | CN | disclosed |
| CN-120136794-A | Evodiamide B and preparation method and application thereof | 江苏省中国科学院植物研究所 | 2025-06-13 | — | — | CN | disclosed |
| CN-120136850-A | Evodiamide C and preparation method and application thereof | 江苏省中国科学院植物研究所 | 2025-06-13 | — | — | CN | disclosed |
| CN-119613411-A | Method for synthesizing coupler aminoketone compound by photocatalysis and application | 贵州大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-116655641-B | Tryptamine ketimine compound and derivative thereof, and synthetic method and application thereof | 成都大学 | 2025-03-11 | — | — | CN | disclosed |
| US-6964960-B2 | Indoloquinazolinones | NOVARTIS AG (CH) | 2005-11-15 | — | — | US | disclosed |
| CN-1183136-C | Indoloquinazolinones | ��˹��ŵ�� | 2005-01-05 | — | — | CN | disclosed |
| EP-1303517-B1 | INDOLOQUINAZOLINONES | NOVARTIS AG (CH) | 2004-03-24 | — | — | EP | disclosed |
| US-20030199502-A1 | Indoloquinazolinones | NOVARTIS AG (CH) | 2003-10-23 | — | — | US | disclosed |
| US-20030199502-A1 | Indoloquinazolinones | NOVARTIS AG (CH) | 2003-10-23 | — | — | US | disclosed |
| CN-1441803-A | Indoloquinazolinones | NOVARTIS AG (CH) | 2003-09-10 | — | — | CN | disclosed |
| EP-1303517-A1 | INDOLOQUINAZOLINONES | Novartis AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002006284-A1 | INDOLOQUINAZOLINONES | NOVARTIS AG (CH) | 2002-01-24 | — | — | WO | disclosed |