Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 6/20 | 0.49 |
| ▸ | TUBAL3 | A6NHL2 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.36 |
| ▸ | TUBA8 | Q9NY65 | 2/20 | 0.36 |
| ▸ | XPO1 | O14980 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | PRNP | P04156 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034952 | 1.00 | PDCD4 (0.49) | PDCD4TUBAL3TUBA3CTUBA1BTUBA4A | |
| SCHEMBL10066911 | 0.83 | PDCD4 (0.46) | PDCD4NPC1RAB9APRNPSMN1; SMN2 | |
| SCHEMBL10066913 | 0.82 | PDCD4 (0.44) | PDCD4TUBAL3TUBA3CTUBA1BTUBA4A | |
| SCHEMBL15618062 | 0.82 | PDCD4 (0.44) | PDCD4TUBAL3TUBA3CTUBA1BTUBA4A | |
| SCHEMBL18850787 | 0.79 | PDCD4 (0.43) | PDCD4TUBAL3TUBA3CTUBA1BTUBA4A | |
| SCHEMBL120200 | 0.72 | — | — | |
| SCHEMBL10990251 | 0.72 | — | — | |
| Ether SCHEMBL11165643 | 0.72 | PDCD4 (0.35) | PDCD4TUBAL3TUBA3CTUBA1BTUBA4A | |
| SCHEMBL17904315 | 0.71 | — | — | |
| SCHEMBL18181596 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971608-B1 | SPIROKETALS | ECOBIOTICS LTD (AU) | 2012-03-14 | — | — | EP | disclosed |