⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9836756 | 0.97 | — | — | |
| SCHEMBL11675772 | 0.87 | CRBN (0.35) | — | |
| SCHEMBL7440465 | 0.78 | — | — | |
| SCHEMBL14218 | 0.76 | — | — | |
| SCHEMBL11675143 | 0.74 | — | — | |
| SCHEMBL8134500 | 0.74 | — | — | |
| Iodide SCHEMBL11062984 | 0.74 | — | — | |
| SCHEMBL27390281 | 0.72 | — | — | |
| SCHEMBL11677321 | 0.72 | TSHR (0.32) | — | |
| SCHEMBL15948670 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215067-A1 | AMINO-HETEROARYL-CONTAINING PROKINETICIN 1 RECEPTOR ANTAGONISTS | Janssen Pharmaceutica, N.V. (BE) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009058653-A1 | AMINO-HETEROARYL-CONTAINING PROKINETICIN 1 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |
| US-6162925-A | Antibiotic for methicillin resistant bacteria | RESEARCH CORPORATION TECH., INC. (US) | 2000-12-19 | — | — | US | disclosed |
| US-6110925-A | EFFECTIVE AGAINST STAPHYLOCOCCUS; ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 2000-08-29 | — | — | US | disclosed |
| EP-1003727-A1 | ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA | RESEARCH CORPORATION TECHNOLOGIES (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007685-A1 | ANTIBIOTIC FOR METHICILLIN RESISTANT BACTERIA | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1999-02-18 | — | — | WO | disclosed |
| US-4290971-A | HYPOTENSIVE AGENTS | DSO "PHARMACHIM" (BG) | 1981-09-22 | — | — | US | disclosed |