Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 5/20 | 0.48 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704380 | 0.84 | CDC7 (0.51) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL3712083 | 0.82 | CDC7 (0.50) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL3708562 | 0.82 | CDC7 (0.50) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL3710935 | 0.81 | CDC7 (0.49) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL3708564 | 0.80 | CDC7 (0.47) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL3708563 | 0.80 | CDC7 (0.47) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL3712738 | 0.79 | CDC7 (0.45) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL3709672 | 0.79 | CDC7 (0.52) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL3707390 | 0.76 | CDC7 (0.58) | CDC7DBF4KDM4EALDH1A1LMNA | |
| SCHEMBL460614 | 0.75 | CDC7 (0.57) | CDC7DBF4KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |