Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 19/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3055974 | 0.88 | STAT3 (0.56) | STAT3PIK3CAPRKAA2 | |
| Bromide SCHEMBL3051472 | 0.85 | STAT3 (0.55) | STAT3PIK3CAPRKAA2 | |
| SCHEMBL3706315 | 0.84 | STAT3 (0.55) | STAT3PIK3CAPRKAA2 | |
| Bromide SCHEMBL3069470 | 0.84 | STAT3 (0.54) | STAT3PIK3CAPRKAA2 | |
| Bromide SCHEMBL3060535 | 0.83 | STAT3 (0.54) | STAT3PIK3CAPRKAA2 | |
| SCHEMBL10180601 | 0.82 | STAT3 (0.62) | STAT3PIK3CAPRKAA2 | |
| Bromide SCHEMBL3069488 | 0.82 | STAT3 (0.52) | STAT3PIK3CAPRKAA2 | |
| Bromide SCHEMBL3054477 | 0.82 | STAT3 (0.62) | STAT3PIK3CAPRKAA2 | |
| Bromide SCHEMBL3057000 | 0.82 | STAT3 (0.56) | STAT3PIK3CAPRKAA2 | |
| Bromide SCHEMBL3051279 | 0.82 | STAT3 (0.57) | STAT3PIK3CAPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009057811-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-05-07 | — | — | WO | disclosed |