Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | PREP | P48147 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630944 | 0.86 | KMT2A (0.60) | MEN1KMT2AALOX15KDM4ETSHR | |
| SCHEMBL1466305 | 0.86 | KMT2A (0.60) | MEN1KMT2AALOX15KDM4ETSHR | |
| SCHEMBL1065002 | 0.86 | MEN1 (0.69) | MEN1KMT2AALOX15KDM4ETSHR | |
| SCHEMBL2019296 | 0.84 | MEN1 (0.67) | MEN1KMT2AALOX15KDM4ETSHR | |
| SCHEMBL2026453 | 0.84 | HDAC1 (0.60) | MEN1KMT2AALOX15KDM4ETSHR | |
| SCHEMBL27991792 | 0.84 | KMT2A (0.62) | MEN1KMT2AALOX15KDM4ETSHR | |
| SCHEMBL31667008 | 0.84 | KMT2A (0.62) | MEN1KMT2AALOX15KDM4ETSHR | |
| SCHEMBL31252762 | 0.82 | KMT2A (0.60) | MEN1KMT2AALOX15KDM4ETSHR | |
| SCHEMBL2024397 | 0.82 | KMT2A (0.60) | MEN1KMT2AALOX15KDM4ETSHR | |
| SCHEMBL31666975 | 0.81 | HDAC1 (0.60) | MEN1KMT2AALOX15KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |