Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.45 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.45 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363326 | 1.00 | CYP19A1 (0.49) | CYP19A1AKR1B10AKR1B1EFNA1EPHA2 | |
| SCHEMBL3363331 | 1.00 | CYP19A1 (0.49) | CYP19A1AKR1B10AKR1B1EFNA1EPHA2 | |
| SCHEMBL5447175 | 1.00 | CYP19A1 (0.49) | CYP19A1AKR1B10AKR1B1EFNA1EPHA2 | |
| SCHEMBL3710947 | 1.00 | CYP19A1 (0.49) | CYP19A1AKR1B10AKR1B1EFNA1EPHA2 | |
| SCHEMBL5447445 | 0.92 | GPBAR1 (0.51) | CYP19A1AKR1B10AKR1B1EFNA1EPHA2 | |
| SCHEMBL3636500 | 0.88 | CYP19A1 (0.48) | CYP19A1AKR1B10AKR1B1EFNA1EPHA2 | |
| SCHEMBL1331512 | 0.86 | CYP19A1 (0.47) | CYP19A1AKR1B10AKR1B1EFNA1EPHA2 | |
| SCHEMBL11520209 | 0.86 | CYP19A1 (0.47) | CYP19A1AKR1B10AKR1B1EFNA1EPHA2 | |
| SCHEMBL9623704 | 0.85 | CYP19A1 (0.46) | CYP19A1AKR1B10AKR1B1EFNA1EPHA2 | |
| SCHEMBL9623701 | 0.85 | CYP19A1 (0.46) | CYP19A1AKR1B10AKR1B1EFNA1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092363-A1 | ASSAY FOR DETECTION OF ADRENAL TUMOUR | THE UNIVERSITY OF BIRMINGHAM (GB) | 2010-08-19 | — | — | WO | disclosed |