Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | MLNR | O43193 | 4/20 | 0.40 |
| ▸ | STAT3 | P40763 | 4/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10181162 | 1.00 | SCN9A (0.49) | SCN9AMGLLMLNRSTAT3CHRM4 | |
| SCHEMBL10181164 | 1.00 | SCN9A (0.49) | SCN9AMGLLMLNRSTAT3CHRM4 | |
| SCHEMBL3050999 | 0.93 | MLNR (0.46) | SCN9AMGLLMLNR | |
| SCHEMBL3066677 | 0.91 | SCN9A (0.59) | SCN9ASTAT3PIK3CAPRKAA2 | |
| SCHEMBL3064516 | 0.89 | SCN9A (0.49) | SCN9AMGLLSTAT3 | |
| SCHEMBL3064521 | 0.89 | SCN9A (0.49) | SCN9AMGLLSTAT3 | |
| SCHEMBL3067772 | 0.89 | SCN9A (0.49) | SCN9AMGLLSTAT3 | |
| Oxalic Acid SCHEMBL3056958 | 0.87 | STAT3 (0.48) | MGLLMLNRSTAT3PIK3CAPRKAA2 | |
| Oxalic Acid SCHEMBL3064025 | 0.87 | STAT3 (0.48) | MGLLMLNRSTAT3PIK3CAPRKAA2 | |
| Oxalic Acid SCHEMBL10181285 | 0.87 | STAT3 (0.48) | MGLLMLNRSTAT3PIK3CAPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | disclosed |
| EP-2207773-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009057811-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-05-07 | — | — | WO | disclosed |