Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570221 | 1.00 | RXFP1 (0.40) | RXFP1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2121820 | 1.00 | RXFP1 (0.40) | RXFP1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2572001 | 0.94 | RXFP1 (0.39) | RXFP1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL479343 | 0.94 | RXFP1 (0.39) | RXFP1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2571388 | 0.93 | CHEK1 (0.38) | RXFP1MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL2122020 | 0.93 | CHEK1 (0.38) | RXFP1MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL3151227 | 0.92 | RXFP1 (0.41) | RXFP1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2119764 | 0.92 | RXFP1 (0.41) | RXFP1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL31093978 | 0.88 | RXFP1 (0.42) | RXFP1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2571239 | 0.88 | RXFP1 (0.42) | RXFP1MAPTRAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |