Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 15/20 | 0.56 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3059553 | 0.99 | STAT3 (0.56) | STAT3PRKAA2PIK3CA | |
| SCHEMBL10180601 | 0.94 | STAT3 (0.62) | STAT3PRKAA2PIK3CA | |
| Oxalic Acid SCHEMBL15295456 | 0.92 | STAT3 (0.60) | STAT3PRKAA2PIK3CA | |
| Bromide SCHEMBL3051279 | 0.89 | STAT3 (0.57) | STAT3PRKAA2PIK3CA | |
| Bromide SCHEMBL3061066 | 0.89 | STAT3 (0.52) | STAT3PRKAA2PIK3CA | |
| Bromide SCHEMBL3054477 | 0.88 | STAT3 (0.62) | STAT3PRKAA2PIK3CA | |
| SCHEMBL3052225 | 0.88 | STAT3 (0.70) | STAT3PRKAA2PIK3CA | |
| Bromide SCHEMBL3051765 | 0.88 | STAT3 (0.49) | STAT3PRKAA2PIK3CA | |
| Bromide SCHEMBL3057000 | 0.88 | STAT3 (0.56) | STAT3PRKAA2PIK3CA | |
| Bromide SCHEMBL3055606 | 0.88 | STAT3 (0.57) | STAT3PRKAA2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-07-21 | — | — | EP | disclosed |
| WO-2009057811-A2 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-05-07 | — | — | WO | disclosed |