Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 6/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716953 | 0.85 | CDC7 (0.48) | CDC7DBF4MAPTALDH1A1KDM4E | |
| SCHEMBL3712724 | 0.85 | CDC7 (0.55) | CDC7DBF4MAPTALDH1A1KDM4E | |
| SCHEMBL3704792 | 0.82 | CDC7 (0.46) | CDC7DBF4MAPTALDH1A1KDM4E | |
| SCHEMBL460614 | 0.80 | CDC7 (0.57) | CDC7DBF4MAPTALDH1A1KDM4E | |
| SCHEMBL3709672 | 0.80 | CDC7 (0.52) | CDC7DBF4MAPTALDH1A1KDM4E | |
| SCHEMBL17309802 | 0.79 | CDC7 (0.56) | CDC7DBF4MAPTALDH1A1KDM4E | |
| SCHEMBL8867203 | 0.79 | CDC7 (0.56) | CDC7DBF4MAPTALDH1A1KDM4E | |
| SCHEMBL8868127 | 0.77 | CDC7 (0.54) | CDC7DBF4MAPTALDH1A1KDM4E | |
| SCHEMBL1986310 | 0.77 | CDC7 (0.51) | CDC7DBF4MAPTALDH1A1KDM4E | |
| SCHEMBL17309789 | 0.76 | CDC7 (0.53) | CDC7DBF4MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |