SCHEMBL371013

SCHEMBL371013

C=CCNC.CN(C)CCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 13/20 0.41
KDM4C Q9H3R0 13/20 0.41
KDM7A Q6ZMT4 2/20 0.41
PHF8 Q9UPP1 2/20 0.41
KDM2A Q9Y2K7 2/20 0.41
KDM5A P29375 1/20 0.41
MAPT P10636 2/20 0.36
ABCC4 O15439 1/20 0.36
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PRMT3 O60678 1/20 0.34
CARM1 Q86X55 1/20 0.34
PRMT6 Q96LA8 1/20 0.34
PRMT1 Q99873 1/20 0.34
PRMT8 Q9NR22 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7600756 0.84 TDP1 (0.34) KDM4AKDM4CKDM7APHF8KDM2A
Bicarbonate SCHEMBL28501524 0.80
SCHEMBL30498495 0.80
SCHEMBL103874 0.80
SCHEMBL30498494 0.80
Acetic Acid SCHEMBL5316671 0.78
Hydrochloric Acid SCHEMBL7336932 0.78 KDM4A (0.55) KDM4AKDM4CKDM7APHF8KDM2A
Iodide SCHEMBL10501551 0.78
Hydrochloric Acid SCHEMBL445971 0.78
SCHEMBL8204155 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030215890-A1 Automated method and reagent therefor assaying body fluid samples such as cerebrospinal fluid (CSF) SIEMENS HEALTHCARE DIAGNOSTICS INC. 2003-11-20 US claimed
EP-0878715-B1 Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers BAYER AG (US) 2002-07-31 EP claimed
US-5858794-A MIXTURE CONTAINING SURFACTANT AND PH BUFFER BAYER CORPORATION (US) 1999-01-12 US claimed
EP-0878715-A1 Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers Bayer Corporation (US) 1998-11-18 EP claimed
EP-2593553-B1 METHODS FOR PRODUCING PROTEINS IN PLANTS PHILIP MORRIS PRODUCTS SA (CH) 2018-03-14 EP disclosed
US-9512439-B2 Methods for producing proteins in plants PHILIP MORRIS PRODUCTS S.A. (CH) 2016-12-06 US disclosed
US-20130205448-A1 METHODS FOR PRODUCING PROTEINS IN PLANTS PHILIP MORRIS PRODUCTS S.A. (CH) 2013-08-08 US disclosed
EP-2593553-A1 METHODS FOR PRODUCING PROTEINS IN PLANTS Philip Morris Products S.A. (CH) 2013-05-22 EP disclosed
WO-2012007587-A1 METHODS FOR PRODUCING PROTEINS IN PLANTS PHILIP MORRIS PRODUCTS S.A. (CH) 2012-01-19 WO disclosed
US-7670798-B2 Automated method and reagent therefor assaying body fluid samples such as cerebrospinal fluid (CSF) SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2010-03-02 US disclosed
EP-1596803-A4 TRANSIENT PRODUCTION OF PHARMACEUTICALLY IMPORTANT PROTEINS IN PLANTS ALTOR BIOSCIENCE CORP (US) 2007-12-12 EP disclosed
EP-1376135-B1 Automated method and reagent therefor for assaying body fluid samples such as cerebrospinal fluid BAYER CORP (US) 2007-04-11 EP disclosed
WO-2005076766-A2 TRANSIENT PRODUCTION OF PHARMACEUTICALLY IMPORTANT PROTEINS IN PLANTS SUNOL MOLECULAR CORPORATION (US) 2005-08-25 WO disclosed
US-20040148656-A1 Transient production of pharmaceutically important proteins in plants SUNOL MOLECULAR CORPORATION 2004-07-29 US disclosed
EP-1376135-A2 Automated method and reagent therefor for assaying body fluid samples such as cerebrospinal fluid BAYER CORPORATION (US) 2004-01-02 EP disclosed
US-20030215890-A1 Automated method and reagent therefor assaying body fluid samples such as cerebrospinal fluid (CSF) SIEMENS HEALTHCARE DIAGNOSTICS INC. 2003-11-20 US disclosed
US-6468732-B1 CROSSLINKER- FREE REAGENT; SODIUM BICARBONATE AND A SPHERING SURFACTANT BAYER CORPORATION 2002-10-22 US disclosed
EP-0878715-B1 Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers BAYER AG (US) 2002-07-31 EP disclosed
US-5858794-A MIXTURE CONTAINING SURFACTANT AND PH BUFFER BAYER CORPORATION (US) 1999-01-12 US disclosed
EP-0878715-A1 Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers Bayer Corporation (US) 1998-11-18 EP disclosed