Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 9/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.49 |
| ▸ | CDK7 | P50613 | 3/20 | 0.49 |
| ▸ | CCNH | P51946 | 3/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.49 |
| ▸ | CDK9 | P50750 | 3/20 | 0.49 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1354895 | 0.91 | CDK2 (0.59) | CDK2CCNE1CDK7CCNHCDK5 | |
| SCHEMBL1354711 | 0.88 | CDK2 (0.60) | CDK2CCNE1CDK7CCNHCDK5 | |
| SCHEMBL3710605 | 0.87 | CDK2 (0.54) | CDK2CCNE1CDK7CCNHCDK5 | |
| SCHEMBL1355496 | 0.85 | CDK2 (0.49) | CDK2CCNE1CDK7CCNHCDK5 | |
| SCHEMBL1354010 | 0.84 | CDK2 (0.59) | CDK2CCNE1CDK7CCNHCDK5 | |
| SCHEMBL1354344 | 0.84 | CDK2 (0.62) | CDK2CCNE1CDK7CCNHCDK5 | |
| SCHEMBL1354652 | 0.84 | CDK2 (0.51) | CDK2CCNE1CDK7CCNHCDK5 | |
| SCHEMBL1354737 | 0.83 | FLT3 (0.60) | CDK2CCNE1CDK7CCNHCDK5 | |
| SCHEMBL1354764 | 0.83 | CDK2 (0.59) | CDK2CCNE1CDK7CCNHCDK5 | |
| SCHEMBL1353872 | 0.83 | CCNE1 (0.62) | CDK2CCNE1CDK7CCNHCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391626-A2 | SUBSTITUTED 6-(2-AMINOBENZYLAMINO)PURINE DERIVATIVES, THEIR USE AS MEDICAMENTS AND PREPARATIONS CONTAINING THESE COMPOUNDS | Univerzita Palackého v Olomouci (CZ) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010085924-A2 | SUBSTITUTED 6-(2-AMINOBENZYLAMINO)PURINE DERIVATIVES, THEIR USE AS MEDICAMENTS AND PREPARATIONS CONTAINING THESE COMPOUNDS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2010-08-05 | — | — | WO | disclosed |