Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2342594 | 0.92 | LPAR1 (0.55) | LPAR1LPAR3LPAR2ENPP2SCN9A | |
| SCHEMBL3704851 | 0.92 | LPAR1 (0.42) | LPAR1LPAR3LPAR2ENPP2SCN9A | |
| SCHEMBL3708661 | 0.90 | LPAR1 (0.55) | LPAR1LPAR3LPAR2ENPP2SCN9A | |
| SCHEMBL3711311 | 0.90 | LPAR1 (0.43) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3714467 | 0.89 | LPAR1 (0.61) | LPAR1LPAR3LPAR2ENPP2SCN9A | |
| SCHEMBL3707179 | 0.88 | LPAR1 (0.48) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3712289 | 0.88 | LPAR1 (0.50) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3709242 | 0.87 | LPAR1 (0.49) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3709683 | 0.87 | SCN9A (0.42) | LPAR1LPAR3LPAR2SCN9ASCN5A | |
| SCHEMBL3705514 | 0.87 | LPAR1 (0.52) | LPAR1LPAR3LPAR2ENPP2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |