Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.64 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389804 | 1.00 | GPBAR1 (0.64) | GPBAR1BRD4CREBBPMEN1KMT2A | |
| SCHEMBL1389584 | 1.00 | GPBAR1 (0.64) | GPBAR1BRD4CREBBPMEN1KMT2A | |
| SCHEMBL1389800 | 1.00 | GPBAR1 (0.64) | GPBAR1BRD4CREBBPMEN1KMT2A | |
| SCHEMBL1389808 | 1.00 | GPBAR1 (0.64) | GPBAR1BRD4CREBBPMEN1KMT2A | |
| SCHEMBL1389586 | 1.00 | GPBAR1 (0.64) | GPBAR1BRD4CREBBPMEN1KMT2A | |
| SCHEMBL1389797 | 1.00 | GPBAR1 (0.64) | GPBAR1BRD4CREBBPMEN1KMT2A | |
| SCHEMBL1389600 | 0.97 | GPBAR1 (0.59) | GPBAR1BRD4CREBBPMEN1KMT2A | |
| SCHEMBL1389603 | 0.97 | GPBAR1 (0.59) | GPBAR1BRD4CREBBPMEN1KMT2A | |
| SCHEMBL1389601 | 0.97 | GPBAR1 (0.59) | GPBAR1BRD4CREBBPMEN1KMT2A | |
| SCHEMBL1389677 | 0.93 | GPBAR1 (0.58) | GPBAR1BRD4CREBBPLMNACTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |